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PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice

Estrogens act in the ventromedial hypothalamic nucleus (VMH) to regulate body weight homeostasis. However, the molecular mechanisms underlying these estrogenic effects are unknown. We show that activation of estrogen receptor-α (ERα) stimulates neural firing of VMH neurons expressing ERα, and these...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Saito, Kenji, He, Yanlin, Yang, Yongjie, Zhu, Liangru, Wang, Chunmei, Xu, Pingwen, Hinton, Antentor Othrell, Yan, Xiaofeng, Zhao, Jean, Fukuda, Makoto, Tong, Qingchun, Clegg, Deborah J., Xu, Yong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796901/
https://ncbi.nlm.nih.gov/pubmed/26988598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23459
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