PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice

Estrogens act in the ventromedial hypothalamic nucleus (VMH) to regulate body weight homeostasis. However, the molecular mechanisms underlying these estrogenic effects are unknown. We show that activation of estrogen receptor-α (ERα) stimulates neural firing of VMH neurons expressing ERα, and these...

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Publicat a:Sci Rep
Autors principals: Saito, Kenji, He, Yanlin, Yang, Yongjie, Zhu, Liangru, Wang, Chunmei, Xu, Pingwen, Hinton, Antentor Othrell, Yan, Xiaofeng, Zhao, Jean, Fukuda, Makoto, Tong, Qingchun, Clegg, Deborah J., Xu, Yong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796901/
https://ncbi.nlm.nih.gov/pubmed/26988598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23459
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