PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice

Estrogens act in the ventromedial hypothalamic nucleus (VMH) to regulate body weight homeostasis. However, the molecular mechanisms underlying these estrogenic effects are unknown. We show that activation of estrogen receptor-α (ERα) stimulates neural firing of VMH neurons expressing ERα, and these...

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Publicado en:Sci Rep
Autores principales: Saito, Kenji, He, Yanlin, Yang, Yongjie, Zhu, Liangru, Wang, Chunmei, Xu, Pingwen, Hinton, Antentor Othrell, Yan, Xiaofeng, Zhao, Jean, Fukuda, Makoto, Tong, Qingchun, Clegg, Deborah J., Xu, Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796901/
https://ncbi.nlm.nih.gov/pubmed/26988598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23459
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