Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons

Studies in humans and rodents indicate that a minimum amount of stored energy is required for normal pubertal development. The adipocyte-derived hormone leptin is a key metabolic signal to the neuroendocrine reproductive axis. Humans and mice lacking leptin or the leptin receptor (LepR) (ob/ob and d...

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Xehetasun bibliografikoak
Egile Nagusiak: Donato, Jose, Cravo, Roberta M., Frazão, Renata, Gautron, Laurent, Scott, Michael M., Lachey, Jennifer, Castro, Inar A., Margatho, Lisandra O., Lee, Syann, Lee, Charlotte, Richardson, James A., Friedman, Jeffrey, Chua, Streamson, Coppari, Roberto, Zigman, Jeffrey M., Elmquist, Joel K., Elias, Carol F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007164/
https://ncbi.nlm.nih.gov/pubmed/21183787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45106
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