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Beyond the SNARE: Munc18-1 chaperones α-synuclein
Early infantile epileptic encephalopathy (EIEE)–associated mutations in MUNC18-1 cause Munc18-1 misfolding and cellular aggregation. In this issue, Chai et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512016) find that Munc18-1 is a molecular chaperone for α-synuclein and that aggregate...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021099/ https://ncbi.nlm.nih.gov/pubmed/27597757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201608060 |
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