טוען...
Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation
Munc18-1 is a key component of the exocytic machinery that controls neurotransmitter release. Munc18-1 heterozygous mutations cause developmental defects and epileptic phenotypes, including infantile epileptic encephalopathy (EIEE), suggestive of a gain of pathological function. Here, we used single...
שמור ב:
| הוצא לאור ב: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021092/ https://ncbi.nlm.nih.gov/pubmed/27597756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201512016 |
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