Učitavanje...
Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity
The accumulation of amyloid β peptide(1–42) (Aβ(1–42)) in extracellular plaques is one of the pathological hallmarks of Alzheimer disease (AD). Several studies have suggested that cellular reuptake of Aβ(1–42) may be a crucial step in its cytotoxicity, but the uptake mechanism is not yet understood....
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016693/ https://ncbi.nlm.nih.gov/pubmed/27458018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691840 |
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