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Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate

Intervention into amyloid deposition with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (AL). In both AL and multiple myeloma (MM), soluble immunoglobulin light chains (LC) are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Andrich, Kathrin, Hegenbart, Ute, Kimmich, Christoph, Kedia, Niraja, Bergen, H. Robert, Schönland, Stefan, Wanker, Erich, Bieschke, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313104/
https://ncbi.nlm.nih.gov/pubmed/28031465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750323
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