Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate

Intervention into amyloid deposition with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (AL). In both AL and multiple myeloma (MM), soluble immunoglobulin light chains (LC) are...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Andrich, Kathrin, Hegenbart, Ute, Kimmich, Christoph, Kedia, Niraja, Bergen, H. Robert, Schönland, Stefan, Wanker, Erich, Bieschke, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313104/
https://ncbi.nlm.nih.gov/pubmed/28031465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750323
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