EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Protein misfolding and formation of β-sheet-rich amyloid fibrils or aggregates is related to cellular toxicity and decay in various human disorders including Alzheimer’s and Parkinson’s disease. Recently, we demonstrated that the polyphenol (-)-epi-gallocatechine gallate (EGCG) inhibits α-synuclein...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Bieschke, Jan, Russ, Jenny, Friedrich, Ralf P., Ehrnhoefer, Dagmar E., Wobst, Heike, Neugebauer, Katja, Wanker, Erich E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867908/
https://ncbi.nlm.nih.gov/pubmed/20385841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910723107
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller