Nalaganje...
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
Protein misfolding and formation of β-sheet-rich amyloid fibrils or aggregates is related to cellular toxicity and decay in various human disorders including Alzheimer’s and Parkinson’s disease. Recently, we demonstrated that the polyphenol (-)-epi-gallocatechine gallate (EGCG) inhibits α-synuclein...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867908/ https://ncbi.nlm.nih.gov/pubmed/20385841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910723107 |
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