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Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress
Cells engage numerous signaling pathways in response to oxidative stress that together repair macromolecular damage or direct the cell toward apoptosis. As a result of DNA damage, mitochondrial DNA or nuclear DNA has been shown to enter the cytoplasm where it binds to “DNA sensors,” which in turn in...
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出版年: | J Biol Chem |
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主要な著者: | , , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016190/ https://ncbi.nlm.nih.gov/pubmed/27369081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.718478 |
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