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Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain
Lymphocyte-specific protein-tyrosine kinase (Lck) plays an essential role in T cell receptor (TCR) signaling and T cell development, but its activation mechanism is not fully understood. To explore the possibility that plasma membrane (PM) lipids control TCR signaling activities of Lck, we measured...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016160/ https://ncbi.nlm.nih.gov/pubmed/27334919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720284 |
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