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Regulation of the Src Family Kinase Lck by Hsp90 and Ubiquitination

Regulation of the Src-related tyrosine kinase Lck is crucial to the outcome of T-cell receptor (TCR) stimulation. It was previously shown that the stability of the constitutively active mutant LckY505F is controlled by Hsp90 (M. J. Bijlmakers and M. Marsh, Mol. Biol. Cell. 11:1585-1595, 2000). Here...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Giannini, Ana, Bijlmakers, Marie-José
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC480905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.13.5667-5676.2004
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