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Regulation of the Src Family Kinase Lck by Hsp90 and Ubiquitination

Regulation of the Src-related tyrosine kinase Lck is crucial to the outcome of T-cell receptor (TCR) stimulation. It was previously shown that the stability of the constitutively active mutant LckY505F is controlled by Hsp90 (M. J. Bijlmakers and M. Marsh, Mol. Biol. Cell. 11:1585-1595, 2000). Here...

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Publicat a:Mol Cell Biol
Autors principals: Giannini, Ana, Bijlmakers, Marie-José
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC480905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.13.5667-5676.2004
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