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Regulation of the Src Family Kinase Lck by Hsp90 and Ubiquitination
Regulation of the Src-related tyrosine kinase Lck is crucial to the outcome of T-cell receptor (TCR) stimulation. It was previously shown that the stability of the constitutively active mutant LckY505F is controlled by Hsp90 (M. J. Bijlmakers and M. Marsh, Mol. Biol. Cell. 11:1585-1595, 2000). Here...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC480905/ https://ncbi.nlm.nih.gov/pubmed/15199125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5667-5676.2004 |
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