Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.

CD4 serves as a receptor for major histocompatibility complex class II antigens and as a receptor for the human immunodeficiency virus type 1 (HIV-1) viral coat protein gp120. It is coupled to the protein-tyrosine kinase p56lck, an interaction necessary for an optimal response of certain T cells to...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Prasad, K V, Kapeller, R, Janssen, O, Repke, H, Duke-Cohan, J S, Cantley, L C, Rudd, C E
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7708-7717.1993
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