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Molecular Basis Behind Inability of Mitochondrial Holocytochrome c Synthase to Mature Bacterial Cytochromes: DEFINING A CRITICAL ROLE FOR CYTOCHROME c α HELIX-1

Mitochondrial holocytochrome c synthase (HCCS) is required for cytochrome c (cyt c) maturation and therefore respiration. HCCS efficiently attaches heme via two thioethers to CXXCH of mitochondrial but not bacterial cyt c even though they are functionally conserved. This inability is due to residues...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Babbitt, Shalon E., Hsu, Jennifer, Kranz, Robert G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016149/
https://ncbi.nlm.nih.gov/pubmed/27387500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.741231
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