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Biosynthesis of single thioether c-type cytochromes provide insight into mechanisms intrinsic to holocytochrome c synthase (HCCS)

c-type cytochromes (cyts c) are generally characterized by the presence of two thioether attachments between heme and two cysteine residues within a highly conserved CXXCH motif. Most eukaryotes use the System III cyt c biogenesis pathway comprised of holocytochrome c synthase (HCCS) to catalyze thi...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Babbitt, Shalon E., Hsu, Jennifer, Mendez, Deanna L., Kranz, Robert G.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551481/
https://ncbi.nlm.nih.gov/pubmed/28617588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00286
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