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Conserved Residues of the Human Mitochondrial Holocytochrome c Synthase Mediate Interactions with Heme

[Image: see text] C-type cytochromes are distinguished by the covalent attachment of a heme cofactor, a modification that is typically required for its subsequent folding, stability, and function. Heme attachment takes place in the mitochondrial intermembrane space and, in most eukaryotes, is mediat...

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Autors principals: Babbitt, Shalon E., San Francisco, Brian, Bretsnyder, Eric C., Kranz, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139152/
https://ncbi.nlm.nih.gov/pubmed/25054239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500704p
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