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Human mitochondrial holocytochrome c synthase’s heme binding, maturation determinants, and complex formation with cytochrome c

Proper functioning of the mitochondrion requires the orchestrated assembly of respiratory complexes with their cofactors. Cytochrome c, an essential electron carrier in mitochondria and a critical component of the apoptotic pathway, contains a heme cofactor covalently attached to the protein at a co...

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Autors principals: San Francisco, Brian, Bretsnyder, Eric C., Kranz, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587199/
https://ncbi.nlm.nih.gov/pubmed/23150584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213897109
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