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XBP1s Is an Anti-lipogenic Protein

Endoplasmic reticulum (ER) stress has been shown to contribute to various metabolic diseases, including non-alcoholic fatty liver disease and type 2 diabetes. Reduction of ER stress by treatment with chemical chaperones or overexpression of ER chaperone proteins alleviates hepatic steatosis. Nonethe...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Herrema, Hilde, Zhou, Yingjiang, Zhang, Dongyan, Lee, Justin, Salazar Hernandez, Mario Andres, Shulman, Gerald I., Ozcan, Umut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016136/
https://ncbi.nlm.nih.gov/pubmed/27325692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728949
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