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IRS1(Ser307) PHOSPHORYLATION DOES NOT MEDIATE mTORC1-INDUCED INSULIN RESISTANCE
Increased mammalian target of rapamycin complex 1 (mTORC1) activity has been suggested to play important roles in development of insulin resistance in obesity. mTORC1 hyperactivity also increases endoplasmic reticulum (ER) stress, which in turn contributes to development of insulin resistance and gl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926104/ https://ncbi.nlm.nih.gov/pubmed/24333417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.12.023 |
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