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Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor tyrosine kinase and are required for hormonal control of metabolism. Tissues from insulin-resistant and diabetic humans exhibit defects in IRS-dependent signalling, implicating their dysregulation in the in...

詳細記述

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書誌詳細
主要な著者: Copps, K. D., White, M. F.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011499/
https://ncbi.nlm.nih.gov/pubmed/22869320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2644-8
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