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LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis
RATIONALE: Human genome wide association studies (GWAS) have revealed novel genetic loci that are associated with coronary heart disease (CHD). One such locus resides in LNK/SH2B3 which in mice is expressed in hematopoietic cells and suppresses thrombopoietin (TPO) signaling via its receptor MPL. Ho...
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| Publicado no: | Circ Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016083/ https://ncbi.nlm.nih.gov/pubmed/27430239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308955 |
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