Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits

BACKGROUND: The chemokine receptors CCR2, CCR5, and CX3CR1 coordinate monocyte trafficking in homeostatic and inflammatory states. Multiple small human genetic studies have variably linked single nucleotide polymorphisms (SNPs) in these genes to cardiometabolic disease. We interrogated genome-wide a...

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Dades bibliogràfiques
Publicat a:Circ Cardiovasc Genet
Autors principals: Golbus, Jessica R., Stitziel, Nathan O., Zhao, Wei, Xue, Chenyi, Farrall, Martin, McPherson, Ruth, Erdmann, Jeanette, Deloukas, Panos, Watkins, Hugh, Schunkert, Heribert, Samani, Nilesh J., Saleheen, Danish, Kathiresan, Sekar, Reilly, Muredach P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015681/
https://ncbi.nlm.nih.gov/pubmed/27013693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.115.001374
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