Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

Monocytes participate critically in atherosclerosis. There are 2 major subsets expressing different chemokine receptor patterns: CCR2(+)CX3CR1(+)Ly-6C(hi) and CCR2(–)CX3CR1(++)Ly-6C(lo) monocytes. Both C-C motif chemokine receptor 2 (CCR2) and C-X(3)-C motif chemokine receptor 1 (CX3CR1) are linked...

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Main Authors: Tacke, Frank, Alvarez, David, Kaplan, Theodore J., Jakubzick, Claudia, Spanbroek, Rainer, Llodra, Jaime, Garin, Alexandre, Liu, Jianhua, Mack, Matthias, van Rooijen, Nico, Lira, Sergio A., Habenicht, Andreas J., Randolph, Gwendalyn J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716202/
https://ncbi.nlm.nih.gov/pubmed/17200718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28549
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