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Leveraging Human Genetics to Guide Drug Target Discovery

Identifying appropriate molecular targets is a critical step in drug development. Despite many advantages, the traditional tools of observational epidemiology and cellular or animal models of disease can be misleading in identifying causal pathways likely to lead to successful therapeutics. Here we...

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Publicat a:Trends Cardiovasc Med
Autors principals: Stitziel, Nathan O., Kathiresan, Sekar
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326691/
https://ncbi.nlm.nih.gov/pubmed/27686272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2016.08.008
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