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P66Shc, a key regulator of metabolism and mitochondrial ROS production, is dysregulated by mouse embryo culture

STUDY QUESTION: Do high oxygen tension and high glucose concentrations dysregulate p66Shc (Src homologous-collagen homologue adaptor protein) expression during mouse preimplantation embryo culture? SUMMARY ANSWER: Compared with mouse blastocysts in vivo, P66Shc mRNA and protein levels in blastocysts...

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書目詳細資料
發表在:Mol Hum Reprod
Main Authors: Edwards, Nicole A., Watson, Andrew J., Betts, Dean H.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013870/
https://ncbi.nlm.nih.gov/pubmed/27385725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaw043
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