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Knockdown of p66Shc Alters Lineage-Associated Transcription Factor Expression in Mouse Blastocysts

The p66Shc adaptor protein regulates apoptosis and senescence during early mammalian development. However, p66Shc expression during mouse preimplantation development is upregulated at the blastocyst stage. Our objective was to determine the biological function of p66Shc during mouse blastocyst devel...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Edwards, Nicole A., Watson, Andrew J., Betts, Dean H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209429/
https://ncbi.nlm.nih.gov/pubmed/30091687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2018.0131
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