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P66SHC and Ageing: ROS and TOR?

Both Reactive Oxygen Species (ROS) and hyperactivation of the nutrient-sensing mTOR/S6 kinase cascade have been linked to aging and age-related diseases as well as to the anti-aging effect of calorie restriction. Recent findings that the pro-aging and pro-oxidant molecule p66shc contributes to S6K a...

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Bibliografski detalji
Glavni autor: Pani, Giovambattista
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954042/
https://ncbi.nlm.nih.gov/pubmed/20689155
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