Valosin-containing protein (VCP)–Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor

Protein quality control (PQC) plays an important role in stemming neurodegenerative diseases and is essential for the growth of some cancers. Valosin-containing protein (VCP)/p97 plays a pivotal role in multiple PQC pathways by interacting with numerous adaptors that link VCP to specific PQC pathway...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Xue, Liang, Blythe, Emily E., Freiberger, Elyse C., Mamrosh, Jennifer L., Hebert, Alexander S., Reitsma, Justin M., Hess, Sonja, Coon, Joshua J., Deshaies, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013311/
https://ncbi.nlm.nih.gov/pubmed/27406709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.061036
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