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Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer
Metabolic reprogramming, in which altered utilization of glucose and glutamine supports rapid growth, is a hallmark of most cancers. Mutations in the oncogenes KRAS and BRAF drive metabolic reprogramming through enhanced glucose uptake, but the broader impact of these mutations on pathways of carbon...
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| Publicado en: | Mol Cell Proteomics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013308/ https://ncbi.nlm.nih.gov/pubmed/27340238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.058925 |
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