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Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins
Plasmepsin IV from Plasmodium falciparum (PM IV) is a promising target for the development of novel antimalarial drugs. Here, the crystal structure of the truncated zymogen of PM IV (pPM IV), consisting of the mature enzyme plus a prosegment of 47 residues, has been determined at 1.5 Å resolution. p...
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| Udgivet i: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012203/ https://ncbi.nlm.nih.gov/pubmed/27599854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16011663 |
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