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Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors

Plasmepsin II (PMII) is one of the ten plasmepsins (PMs) identified in the genome of Plasmodium falciparum, the causative agent of the most severe and deadliest form of malaria. Owing to the emergence of P. falciparum strains that are resistant to current antimalarial agents such as chloroquine and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Acta Crystallogr F Struct Biol Commun
मुख्य लेखकों: Recacha, Rosario, Leitans, Janis, Akopjana, Inara, Aprupe, Lilija, Trapencieris, Peteris, Jaudzems, Kristaps, Jirgensons, Aigars, Tars, Kaspars
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: International Union of Crystallography 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666482/
https://ncbi.nlm.nih.gov/pubmed/26625296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15022049
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