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Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors
Plasmepsin II (PMII) is one of the ten plasmepsins (PMs) identified in the genome of Plasmodium falciparum, the causative agent of the most severe and deadliest form of malaria. Owing to the emergence of P. falciparum strains that are resistant to current antimalarial agents such as chloroquine and...
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| Publié dans: | Acta Crystallogr F Struct Biol Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
International Union of Crystallography
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666482/ https://ncbi.nlm.nih.gov/pubmed/26625296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15022049 |
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