Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors

Plasmepsin II (PMII) is one of the ten plasmepsins (PMs) identified in the genome of Plasmodium falciparum, the causative agent of the most severe and deadliest form of malaria. Owing to the emergence of P. falciparum strains that are resistant to current antimalarial agents such as chloroquine and...

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Detaylı Bibliyografya
Yayımlandı:Acta Crystallogr F Struct Biol Commun
Asıl Yazarlar: Recacha, Rosario, Leitans, Janis, Akopjana, Inara, Aprupe, Lilija, Trapencieris, Peteris, Jaudzems, Kristaps, Jirgensons, Aigars, Tars, Kaspars
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2015
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666482/
https://ncbi.nlm.nih.gov/pubmed/26625296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15022049
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