Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum

The de novo pyrimidine-biosynthesis pathway of Plasmodium falciparum is a promising target for antimalarial drug discovery. The parasite requires a supply of purines and pyrimidines for growth and proliferation and is unable to take up pyrimidines from the host. Direct (or indirect) inhibition of de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Crystallogr F Struct Biol Commun
Egile Nagusiak: Lunev, Sergey, Bosch, Soraya S., Batista, Fernando de Assis, Wrenger, Carsten, Groves, Matthew R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2016
Gaiak:
Research Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933002/
https://ncbi.nlm.nih.gov/pubmed/27380369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16008475
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