Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum

Aspartate aminotransferases (EC 2.6.1.1) catalyse the conversion of aspartate and α-ketoglutarate to oxaloacetate and glutamate in a reversible manner. Thus, the aspartate aminotransferase of Plasmodium falciparum (PfAspAT) plays a central role in the transamination of amino acids. Recent findings s...

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Bibliografiske detaljer
Main Authors: Jain, Rishabh, Jordanova, Rositsa, Müller, Ingrid B., Wrenger, Carsten, Groves, Matthew R.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2010
Fag:
Crystallization Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852332/
https://ncbi.nlm.nih.gov/pubmed/20383010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110003933
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