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Protein kinase A inhibition of macrophage maturation is accompanied by an increase in DNA methylation of the colony‐stimulating factor 1 receptor gene

Macrophage colony‐stimulating factor 1 (CSF‐1) plays a critical role in the differentiation of mononuclear phagocytes from bone marrow precursors, and maturing monocytes and macrophages exhibit increased expression of the CSF‐1 receptor, CSF1R. The expression of CSF1R is tightly regulated by transcr...

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Publicado en:Immunology
Autores principales: Zasłona, Zbigniew, Scruggs, Anne M., Peters‐Golden, Marc, Huang, Steven K.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011683/
https://ncbi.nlm.nih.gov/pubmed/27353657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12641
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