Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure

Extensive convergent evidence collectively suggests that mitochondrial dysfunction is central to the pathogenesis of Parkinson’s disease (PD). Recently, changes in the dynamic properties of mitochondria have been increasingly implicated as a key proximate mechanism underlying neurodegeneration. Howe...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Dukes, April A., Bai, Qing, Van Laar, Victor S., Zhou, Yangzhong, Ilin, Vladimir, David, Christopher N., Agim, Zeynep S., Bonkowsky, Joshua L., Cannon, Jason R., Watkins, Simon C., St. Croix, Claudette M., Burton, Edward A., Berman, Sarah B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010936/
https://ncbi.nlm.nih.gov/pubmed/27452482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.07.020
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