Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure

Extensive convergent evidence collectively suggests that mitochondrial dysfunction is central to the pathogenesis of Parkinson’s disease (PD). Recently, changes in the dynamic properties of mitochondria have been increasingly implicated as a key proximate mechanism underlying neurodegeneration. Howe...

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Vydáno v:Neurobiol Dis
Hlavní autoři: Dukes, April A., Bai, Qing, Van Laar, Victor S., Zhou, Yangzhong, Ilin, Vladimir, David, Christopher N., Agim, Zeynep S., Bonkowsky, Joshua L., Cannon, Jason R., Watkins, Simon C., St. Croix, Claudette M., Burton, Edward A., Berman, Sarah B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010936/
https://ncbi.nlm.nih.gov/pubmed/27452482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.07.020
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