Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure

Extensive convergent evidence collectively suggests that mitochondrial dysfunction is central to the pathogenesis of Parkinson’s disease (PD). Recently, changes in the dynamic properties of mitochondria have been increasingly implicated as a key proximate mechanism underlying neurodegeneration. Howe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurobiol Dis
Prif Awduron: Dukes, April A., Bai, Qing, Van Laar, Victor S., Zhou, Yangzhong, Ilin, Vladimir, David, Christopher N., Agim, Zeynep S., Bonkowsky, Joshua L., Cannon, Jason R., Watkins, Simon C., St. Croix, Claudette M., Burton, Edward A., Berman, Sarah B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010936/
https://ncbi.nlm.nih.gov/pubmed/27452482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.07.020
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