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MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts

TNF-α is a major cytokine implicated in rheumatoid arthritis (RA). TNF-α expression is shown to be regulated at transcriptional as well as posttranscriptional levels. However, the impact of changes in microRNA (miRNA) expression on posttranslational processes involved in TNF-α signaling networks is...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Akhtar, Nahid, Singh, Anil Kumar, Ahmed, Salahuddin
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010933/
https://ncbi.nlm.nih.gov/pubmed/27534557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600360
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