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MicroRNA-17 Suppresses TNF-α Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts
TNF-α is a major cytokine implicated in rheumatoid arthritis (RA). TNF-α expression is shown to be regulated at transcriptional as well as posttranscriptional levels. However, the impact of changes in microRNA (miRNA) expression on posttranslational processes involved in TNF-α signaling networks is...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010933/ https://ncbi.nlm.nih.gov/pubmed/27534557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600360 |
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