Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer

Brain metastasis is one of the chief causes of mortality in breast cancer patients, but the mechanisms that drive this process remains poorly understood. Here we report that brain metastatic cells expressing high levels of c-Met promote the metastatic process via inflammatory cytokine upregulation a...

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Publicado en:Cancer Res
Main Authors: Xing, Fei, Liu, Yin, Sharma, Sambad, Wu, Kerui, Chan, Michael D., Lo, Hui-Wen, Carpenter, Richard L., Metheny-Barlow, Linda J., Zhou, Xiaobo, Qasem, Shadi A., Pasche, Boris, Watabe, Kounosuke
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010459/
https://ncbi.nlm.nih.gov/pubmed/27364556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3541
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