BSCI-13. TUMOR-SPECIFIC tGLI1 TRANSCRIPTION FACTOR MEDIATES BREAST CANCER BRAIN METASTASIS VIA ACTIVATING METASTASIS-INITIATING CANCER STEM CELLS AND ASTROCYTES IN THE TUMOR MICROENVIRONMENT

Breast cancer is the second leading cause of brain metastases in women; patients with breast cancer brain metastasis (BCBM) survive only 6–18 months after diagnosis. Mechanisms for BCBM remain unclear, which contributes to ineffective treatments and dismal prognosis. Truncated glioma-associated onco...

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Veröffentlicht in:Neurooncol Adv
Hauptverfasser: Sirkisoon, Sherona, Carpenter, Richard, Rimkus, Tadas, Doheny, Daniel, Zhu, Dongqin, Aguayo, Noah, Anguelov, Marlyn, Arrigo, Austin, Regua, Angelina, Xing, Fei, Chan, Michael, Metheny-Barlow, Linda, Watabe, Kounosuke, Lo, Hui-Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213263/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.011
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