Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer

Brain metastasis is one of the chief causes of mortality in breast cancer patients, but the mechanisms that drive this process remains poorly understood. Here we report that brain metastatic cells expressing high levels of c-Met promote the metastatic process via inflammatory cytokine upregulation a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res
Prif Awduron: Xing, Fei, Liu, Yin, Sharma, Sambad, Wu, Kerui, Chan, Michael D., Lo, Hui-Wen, Carpenter, Richard L., Metheny-Barlow, Linda J., Zhou, Xiaobo, Qasem, Shadi A., Pasche, Boris, Watabe, Kounosuke
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010459/
https://ncbi.nlm.nih.gov/pubmed/27364556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3541
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