Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer

Brain metastasis is one of the chief causes of mortality in breast cancer patients, but the mechanisms that drive this process remains poorly understood. Here we report that brain metastatic cells expressing high levels of c-Met promote the metastatic process via inflammatory cytokine upregulation a...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Xing, Fei, Liu, Yin, Sharma, Sambad, Wu, Kerui, Chan, Michael D., Lo, Hui-Wen, Carpenter, Richard L., Metheny-Barlow, Linda J., Zhou, Xiaobo, Qasem, Shadi A., Pasche, Boris, Watabe, Kounosuke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010459/
https://ncbi.nlm.nih.gov/pubmed/27364556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3541
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