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Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer

Brain metastasis is one of the chief causes of mortality in breast cancer patients, but the mechanisms that drive this process remains poorly understood. Here we report that brain metastatic cells expressing high levels of c-Met promote the metastatic process via inflammatory cytokine upregulation a...

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Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Xing, Fei, Liu, Yin, Sharma, Sambad, Wu, Kerui, Chan, Michael D., Lo, Hui-Wen, Carpenter, Richard L., Metheny-Barlow, Linda J., Zhou, Xiaobo, Qasem, Shadi A., Pasche, Boris, Watabe, Kounosuke
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010459/
https://ncbi.nlm.nih.gov/pubmed/27364556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3541
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