In vivo evidence for translesion synthesis by the replicative DNA polymerase δ

The intolerance of DNA polymerase δ (Polδ) to incorrect base pairing contributes to its extremely high accuracy during replication, but is believed to inhibit translesion synthesis (TLS). However, chicken DT40 cells lacking the POLD3 subunit of Polδ are deficient in TLS. Previous genetic and biochem...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Hirota, Kouji, Tsuda, Masataka, Mohiuddin, Tsurimoto, Toshiki, Cohen, Isadora S., Livneh, Zvi, Kobayashi, Kaori, Narita, Takeo, Nishihara, Kana, Murai, Junko, Iwai, Shigenori, Guilbaud, Guillaume, Sale, Julian E., Takeda, Shunichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009730/
https://ncbi.nlm.nih.gov/pubmed/27185888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw439
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky