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Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling
Peripheral macrophages and resident microglia constitute the dominant glioma-infiltrating cells. The tumor induces an immunosuppressive and tumor-supportive phenotype in these glioma-associated microglia/brain macrophages (GAMs). A subpopulation of glioma cells acts as glioma stem cells (GSCs). We e...
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Publicat a: | J Neuropathol Exp Neurol |
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Autors principals: | , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2016
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009477/ https://ncbi.nlm.nih.gov/pubmed/27030742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw016 |
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