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Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling

BACKGROUND: Accumulation and infiltration of microglia/brain macrophages around and into glioma tissue promote tumor invasion and expansion. One tumor-promoting mechanism of microglia/brain macrophages is upregulation of membrane type 1 matrix metalloprotease (MT1-MMP), which promotes the degradatio...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hu, Feng, a Dzaye, Omar Dildar, Hahn, Alexander, Yu, Yong, Scavetta, Rick Joey, Dittmar, Gunnar, Kaczmarek, Adrian Kamil, Dunning, Kylie R., Ricciardelli, Carmela, Rinnenthal, Jan L., Heppner, Frank L., Lehnardt, Seija, Synowitz, Michael, Wolf, Susanne A., Kettenmann, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288527/
https://ncbi.nlm.nih.gov/pubmed/25452390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou324
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