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Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling

BACKGROUND: Accumulation and infiltration of microglia/brain macrophages around and into glioma tissue promote tumor invasion and expansion. One tumor-promoting mechanism of microglia/brain macrophages is upregulation of membrane type 1 matrix metalloprotease (MT1-MMP), which promotes the degradatio...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Hu, Feng, a Dzaye, Omar Dildar, Hahn, Alexander, Yu, Yong, Scavetta, Rick Joey, Dittmar, Gunnar, Kaczmarek, Adrian Kamil, Dunning, Kylie R., Ricciardelli, Carmela, Rinnenthal, Jan L., Heppner, Frank L., Lehnardt, Seija, Synowitz, Michael, Wolf, Susanne A., Kettenmann, Helmut
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288527/
https://ncbi.nlm.nih.gov/pubmed/25452390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou324
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